3  Step 0: Analytic data

3.1 Merge 2013-18 datasets

Data from 3 cycles are merged based on available covariates.

Only complete cases retained, and survey features/weights were ignored for simplicity.

3.2 Summary statistics

No
(N=8087)
Yes
(N=5418)
Overall
(N=13505)
age.cat
20-49 4076 (50.4%) 2649 (48.9%) 6725 (49.8%)
50-64 2048 (25.3%) 1558 (28.8%) 3606 (26.7%)
65+ 1963 (24.3%) 1211 (22.4%) 3174 (23.5%)
sex
Male 4125 (51.0%) 2352 (43.4%) 6477 (48.0%)
Female 3962 (49.0%) 3066 (56.6%) 7028 (52.0%)
education
Less than high school 1609 (19.9%) 1132 (20.9%) 2741 (20.3%)
High school 4111 (50.8%) 3237 (59.7%) 7348 (54.4%)
College graduate or above 2367 (29.3%) 1049 (19.4%) 3416 (25.3%)
race
White 3159 (39.1%) 2086 (38.5%) 5245 (38.8%)
Black 1420 (17.6%) 1338 (24.7%) 2758 (20.4%)
Hispanic 1780 (22.0%) 1540 (28.4%) 3320 (24.6%)
Others 1728 (21.4%) 454 (8.4%) 2182 (16.2%)
marital
Never married 1519 (18.8%) 916 (16.9%) 2435 (18.0%)
Married/with partner 4924 (60.9%) 3227 (59.6%) 8151 (60.4%)
Other 1644 (20.3%) 1275 (23.5%) 2919 (21.6%)
income
less than $20,000 1524 (18.8%) 1091 (20.1%) 2615 (19.4%)
$20,000 to $74,999 4058 (50.2%) 2966 (54.7%) 7024 (52.0%)
$75,000 and Over 2505 (31.0%) 1361 (25.1%) 3866 (28.6%)
born
Born in US 5247 (64.9%) 4193 (77.4%) 9440 (69.9%)
Other place 2840 (35.1%) 1225 (22.6%) 4065 (30.1%)
year
Mean (SD) 8.93 (0.812) 8.99 (0.809) 8.95 (0.812)
Median [Min, Max] 9.00 [8.00, 10.0] 9.00 [8.00, 10.0] 9.00 [8.00, 10.0]
diabetes.family.history
No 6739 (83.3%) 4087 (75.4%) 10826 (80.2%)
Yes 1348 (16.7%) 1331 (24.6%) 2679 (19.8%)
smoking
Never smoker 4654 (57.5%) 3074 (56.7%) 7728 (57.2%)
Previous smoker 1795 (22.2%) 1435 (26.5%) 3230 (23.9%)
Current smoker 1638 (20.3%) 909 (16.8%) 2547 (18.9%)
diet.healthy
Poor or fair 1981 (24.5%) 2261 (41.7%) 4242 (31.4%)
Good 3346 (41.4%) 2153 (39.7%) 5499 (40.7%)
Very good or excellent 2760 (34.1%) 1004 (18.5%) 3764 (27.9%)
physical.activity
No 6445 (79.7%) 4167 (76.9%) 10612 (78.6%)
Yes 1642 (20.3%) 1251 (23.1%) 2893 (21.4%)
medical.access
No 1546 (19.1%) 762 (14.1%) 2308 (17.1%)
Yes 6541 (80.9%) 4656 (85.9%) 11197 (82.9%)
sleep
Mean (SD) 7.41 (1.53) 7.32 (1.61) 7.37 (1.56)
Median [Min, Max] 7.50 [2.00, 14.5] 7.00 [2.00, 14.0] 7.50 [2.00, 14.5]
systolicBP
Mean (SD) 123 (18.8) 127 (17.3) 125 (18.4)
Median [Min, Max] 119 [64.7, 229] 125 [74.0, 234] 122 [64.7, 234]
diastolicBP
Mean (SD) 70.0 (11.3) 72.2 (11.8) 70.9 (11.6)
Median [Min, Max] 70.0 [8.00, 123] 72.0 [26.0, 125] 70.7 [8.00, 125]
uric.acid
Mean (SD) 5.20 (1.37) 5.77 (1.49) 5.43 (1.45)
Median [Min, Max] 5.10 [0.700, 12.3] 5.70 [1.60, 18.0] 5.30 [0.700, 18.0]
protein.total
Mean (SD) 7.14 (0.466) 7.11 (0.449) 7.13 (0.459)
Median [Min, Max] 7.10 [4.70, 10.2] 7.10 [5.20, 9.40] 7.10 [4.70, 10.2]
bilirubin.total
Mean (SD) 0.581 (0.302) 0.511 (0.288) 0.553 (0.298)
Median [Min, Max] 0.500 [0, 3.30] 0.500 [0, 7.10] 0.500 [0, 7.10]
phosphorus
Mean (SD) 3.72 (0.560) 3.65 (0.575) 3.69 (0.567)
Median [Min, Max] 3.70 [1.00, 9.60] 3.60 [1.70, 8.90] 3.70 [1.00, 9.60]
sodium
Mean (SD) 140 (2.47) 139 (2.52) 140 (2.49)
Median [Min, Max] 140 [124, 161] 139 [119, 154] 140 [119, 161]
potassium
Mean (SD) 4.00 (0.361) 4.02 (0.356) 4.01 (0.359)
Median [Min, Max] 4.00 [2.63, 6.00] 4.00 [2.60, 6.60] 4.00 [2.60, 6.60]
globulin
Mean (SD) 2.87 (0.449) 3.00 (0.452) 2.92 (0.455)
Median [Min, Max] 2.80 [1.60, 6.50] 3.00 [1.40, 5.70] 2.90 [1.40, 6.50]
calcium.total
Mean (SD) 9.39 (0.366) 9.32 (0.370) 9.36 (0.369)
Median [Min, Max] 9.40 [6.40, 14.8] 9.30 [6.60, 12.0] 9.40 [6.40, 14.8]
high.cholesterol
No 5436 (67.2%) 3271 (60.4%) 8707 (64.5%)
Yes 2651 (32.8%) 2147 (39.6%) 4798 (35.5%)

Investigator specified covariates stratified by the exposure (obesity)