Q1. What is the appropriate way to justify the causal and relational assumptions behind the mediation analysis?
- A. Significance/hypothesis testing always at 5% level of significance.
- B. Use standardized mean difference, with cut point 0.1 or 0.2.
- C. Use subject-area expertise / knowledge to explain/justify the causal and biological mechanism and relationships as much as possible.
- D. Impute missing variables if they are not measured at baseline.