Advanced Epidemiological Methods

Authors
Affiliations

M. Ehsan. Karim

School of Population and Public Health, The University of British Columbia

Epi-OER team

Epi-OER team includes co-applicants of the UBC OER Fund Implementation Grant - Hossain MB, Frank HA, Yusuf FL, Ahmed SS, Asamoah-Boaheng M, Zheng C (all affiliated with the University of British Columbia)

Published

April 20, 2024

The Project

Welcome to a website designed to bridge a unique gap in the health research world. This platform specifically targets the complex intersection of health research and advanced statistics; a niche often perceived as challenging by many newcomers. Whether you’re taking your first steps into health research or you’re grappling with the intricacies of advanced statistical methods, you are in the right place. Here, we offer:

  • Tutorials on using the R software, starting from the basics.
  • Guides on tapping into genuine survey data from reputable sources like Statistics Canada and the US government’s Centers for Disease Control (CDC).
  • Step-by-step walkthroughs on conducting and reporting comprehensive epidemiological studies.

This hub is a part of an open educational initiative, meaning it is available to everyone. We hope to raise the standard of health research methodology through this endeavor.

What We Aim to Achieve

We are on a mission to:

  • Equip public health learners with hands-on experience.
  • Teach the nuances of applying advanced epidemiological methods using real data.
  • Offer a unique open textbook that’s enriched with interactive tools and quizzes for a self-paced learning experience.

Dive into Our Modules

Embark on a journey through

  • 1 introductory module about R (indicator W),
  • 9 core learning modules (letters in the parentheses: A, Q, R, P, D, M, S, L, C are the chapter indicators), and
  • 4 bonus modules, with N, T, I, G being bonus chapter indicators.

Indicators are listed along with quizzes, R functions, and exercises associated with the corresponding chapters. Only key chapters have exercises (W, A, D, M, S).

Module Topics.Indicators Descriptions
1 R for Data Wrangling (W) Get to know R.
2 Accessing (A) Survey Data Resources Understand and source reliable national survey data.
3 Crafting Analytic Data for Research Questions (Q) Customize data to your research query.
4 Causal Roles (R) Delve into the concept of confounding and its implications.
5 Predictive (P) modeling Introduction to key concepts of prediction modelling.
6 Complex Survey Data (D) Analysis Handle data sets obtained from complex survey designs.
7 Missing (M) Data Analysis Understand and tackle missingness in your data.
8 Propensity Score (S) Analysis Dive deeper into advanced observational data analyses.
9 Machine Learning (L) Introduction to machine learning algorithms, and applications.
10 Intergrating Machine Learners in Causal (C) Inference Discusses the potential pitfalls and challenges in merging machine learning with causal inference, and a way forward.
11 Non-binary Outcomes (N) Statistical techniques to deal with complex or non-binary outcomes
12 Longitudinal Analysis (T) Longitudinal data analysis techniques
13 Mediation Analysis (I) Mediation: decomposing the total effect
14 Scientific Writing Tools (G) Tools and guides for scientific writing and collaboration.
Note

The tutorial is designed with a consistent structure across all chapters to provide a cohesive and thorough learning experience. Here is what you can expect in each chapter:

  1. Overview: The first page of each chapter offers a concise summary that outlines the key learning objectives, topics covered, and what you can expect to gain from the chapter. The overview page will also feature links to the data sources used in the tutorials as well as a form where you can report any bugs or issues you encounter. This helps you quickly grasp the chapter’s essence and set learning expectations.

  2. Concepts: Selected core chapters will include a concept page, where materials (e.g., slides, video lessons, additional FAQs where available) will be included. All of the videos linked here (for lessons or labs) are hosted in YouTube, where users can automatically generate subtitles and captions.

  3. Tutorial topics: Immediately following the overview/concepts, you will find in-depth tutorials that cover each topic in detail. These are designed to provide comprehensive insights and are spread across multiple pages for easier navigation and understanding.

  4. Summary of R functions: Each chapter includes a succinct summary of the R functions used in the tutorials. This serves as a quick reference guide for learners to understand the tools they will be applying.

  5. Chapter-specific quiz: For those interested in self-assessment, each chapter concludes with an optional quiz. This is a self-paced learning tool to help reinforce the chapter’s key concepts.

  6. Web-App: A few chapters include shiny apps. Users can work with these apps directly from this website, or will have the option to download and run the app locally.

  7. Practice exercises: Finally, practice exercises are available for selected chapters to help you apply what you have learned in a hands-on manner. These exercises are designed to reinforce your understanding and give you practical experience with the chapter’s topics. Some of these practice exercises may be used in future versions of the course, so you may see references to submitting assignments or the points value of a question in an assignment.

How Our Content is Presented

All our resources are hosted on an easy-to-access GitHub page. The format? Engaging text, reproducible software codes, clear analysis outputs, and crisp videos that distill complex topics. And do not miss our quiz section at the end of each module for a quick self-check on what you have learned. This document is created using quarto and R.

The content was primarily designed for a website in HTML format; however, a PDF version based on the website has also been created. Although the formatting is not perfect for this converted PDF, this PDF can be downloaded from here and used for offline reading.

Grant Applicants

Dive into this captivating content, brought to life with the generous support of the UBC OER Fund Implementation Grant and further supported by UBC SPPH. The foundation of this content traces back to the PI’s work over five years while instructing SPPH 604 (2018-2022). That knowledge has now been transformed into an open educational resource, thanks to this grant. Meet the innovative minds behind the grant proposal below.

Role Team_Member Affiliation
Principal Applicant (PI) Dr. M Ehsan Karim UBC School of Population and Public Health
Co-applicant (Co-I) Dr. Suborna Ahmed UBC Department of Forest Resources Management
Trainee co-applicants Md Belal Hossain UBC School of Population and Public Health
Fardowsa Yusuf UBC School of Population and Public Health
Hanna Frank UBC School of Population and Public Health
Dr. Michael Asamoah-Boaheng UBC Department of Emergency Medicine
Chuyi (Astra) Zheng UBC Faculty of Arts

A presentation about the output of this grant in the OER Project Virtual Showcase and Poster Session (March 7, 2024):

Acknowledgements

We also want to acknowledge earlier contributors to the course material development, who were not part of this current OER grant, include Derek Ouyang, Kate McLeod (both from UBC School of Population and Public Health), and Mohammad Atiquzzaman (UBC Pharmaceutical Sciences). Numerous pieces of student feedback were also incorporated in order to update the content.

How to Cite

Style Citation
APA Karim M. E., Epi-OER team ( 2024 ). Advanced Epidemiological Methods . Retrieved from https://ehsanx.github.io/EpiMethods/ on April 20, 2024 .
MLA Karim M. E., Epi-OER team . " Advanced Epidemiological Methods ." Web. April 20, 2024 < https://ehsanx.github.io/EpiMethods/ >.
Chicago Karim M. E., Epi-OER team . " Advanced Epidemiological Methods ." 2024 . Web. April 20, 2024 < https://ehsanx.github.io/EpiMethods/ >.
Harvard Karim M. E., Epi-OER team ( 2024 ) ' Advanced Epidemiological Methods '. Available at: https://ehsanx.github.io/EpiMethods/ (Accessed: April 20, 2024 ).
Vancouver Karim M. E., Epi-OER team . Advanced Epidemiological Methods . 2024 . [Online]. Available at: https://ehsanx.github.io/EpiMethods/ (Accessed April 20, 2024 ).
IEEE Karim M. E., Epi-OER team , " Advanced Epidemiological Methods ," 2024 , [Online]. Available: https://ehsanx.github.io/EpiMethods/ . Accessed on: April 20, 2024 .
AMA Karim M. E., Epi-OER team Advanced Epidemiological Methods . 2024 . [Online]. Available at: https://ehsanx.github.io/EpiMethods/ (Accessed April 20, 2024 ).
  • Epi-OER team: Hossain MB, Frank HA, Yusuf FL, Ahmed SS, Asamoah-Boaheng M, Zheng C (team is listed in order of contribution to the creation of this book)

The BibTex format can be downloaded from here.